There are currently no known drug interactions with GG-PRIME™.  As always, please consult with a healthcare professional prior to starting any dietary supplement. 

Active Ingredients: Geranylgeraniol 150 mg

Inactive Ingredients: Gelatin, Glycerin, Purified water

Statin Users: All statin users could benefit by supplementing with GG-PRIME™. It's the perfect companion to statins.

Adults 65+: GG levels decline with age, so supplementation can help maintain cellular energy, muscle health, and bone density.

1 capsule per day with a meal. May take one additional capsule per day as directed by a healthcare professional. Not to exceed 2 capsules daily. 

Taking with food enhances the absorption since GG-PRIME™ is fat soluble.

Time of day does not make a significant difference. We recommend trying to stay consistent.

Based on current research there are no major side effects reported from taking geranylgeraniol (GG) supplements. Here are the key points regarding the safety and side effects of GG supplementation:

1. A toxicological evaluation study [2] found no adverse effects of GG even at high doses in animal models, suggesting a good safety profile.

2. A randomized, placebo-controlled trial in healthy adults [3] specifically investigated the effects of escalating doses of GG (up to 1200 mg/day) on blood safety parameters and sex hormone profiles. No significant adverse events or side effects were reported by participants taking GG supplements compared to placebo.

3. The study [3] monitored for potential side effects like headache, dizziness, nausea, vomiting, heart palpitations, and trouble sleeping, but found no increased incidence with GG supplementation.

4. The search results do not mention any specific side effects associated with GG supplementation in humans. Instead, they highlight the potential benefits of GG in mitigating statin-induced muscle symptoms and other side effects [1][4][5].

Therefore, based on the available evidence, geranylgeraniol appears to be well-tolerated and safe for supplementation, with no significant side effects reported in human studies or toxicological evaluations[2][3]. However, it is always advisable to consult with a healthcare professional before starting any new supplement, especially for individuals with pre-existing medical conditions or taking other medications.

Sources

[1] Geranylgeraniol Supplements: A Game-changer For Statin Toxicity ... https://wellnessextract.com/blogs/wellness/geranylgeraniol-supplements-a-game-changer-for-statin-toxicity-management

[2] A New Supplement Brings Many Health Benefits: GG https://www.wholefoodsmagazine.com/articles/3268-a-new-supplement-brings-many-health-benefits-gg

[3] The Effects of Geranylgeraniol on Blood Safety and Sex Hormone ... https://www.mdpi.com/1661-3821/3/4/43

[4] Oral Administration of Geranylgeraniol Rescues Denervation ... https://iv.iiarjournals.org/content/34/5/2345

[5] Health Benefits And Uses Of Geranylgeraniol - Xtend-Life https://www.xtend-life.com/blogs/supplement-ingredients/geranylgeraniol

The active ingredient in GG-PRIME™

Geranylgeraniol (GG) is an important biomolecule with the following key characteristics:

1. GG is an endogenous nutrient produced in the human body via the mevalonate pathway, the same biochemical pathway that produces cholesterol, CoQ10, and other essential compounds.

2. It is a 20-carbon isoprenoid compound that serves as a precursor for the synthesis of various biomolecules like carotenoids, vitamins, and chlorophyll and hemoglobin in plants and animals.

3. In the body, GG is converted to its activated form geranylgeranyl pyrophosphate (GGPP), which is involved in a process called protein prenylation or geranylgeranylation.

4. Protein prenylation facilitates the membrane association and activation of numerous proteins, particularly small GTPases like Rho and Ras, which regulate critical cellular processes like protein synthesis, cell proliferation, and mitochondrial function.

5. GG levels decline with aging, and certain medications like statins (cholesterol-lowering drugs) and bisphosphonates (osteoporosis drugs) inhibit the mevalonate pathway, reducing endogenous GG production.

6. Supplementation with exogenous GG has been proposed as a strategy to replenish depleted GG levels, mitigate statin side effects like muscle pain/weakness, restore CoQ10 levels, support healthy aging, and potentially provide other benefits related to hormone regulation and bone health.

In summary, GG is an essential nutrient produced endogenously that plays a crucial role in various cellular processes through protein prenylation. Supplementation with GG may help counteract age-related and drug-induced GG depletion, with potential applications in managing statin side effects, supporting mitochondrial function, and promoting healthy aging.

Statins can deplete levels of GG and, leading to muscle pain, weakness, and reduced cellular energy (coQ10). GG helps replenish these levels, supporting mitochondrial function, muscle health, and overall energy production.

Additionally, GG plays a crucial role in synthesizing important compounds like vitamin K2 (MK4) and steroid hormones, which can further aid in maintaining bone health and hormonal balance.

There is no evidence to suggest that GG has any effect on cholesterol. The research shows GG being cardioprotective.

Since GG is made after the Cholesterol branching step, there is no effect on statins ability to lower cholesterol.

The time to notice benefits from GG-PRIME™ can vary depending on individual health conditions and the consistency of use. Some may notice improvements in a few weeks, while for others, it may take longer.

GG-PRIME™ is sourced directly from American River Nutrition LLC, GG-Gold™. It is physically derived from the South American native Annatto plant without the use of chemical solvents or additional additives and made here in the United States at a certified cGMP facility.

The result is a naturally derived source of pure geranylgeraniol.

Each batch undergoes testing to ensure quality standards.

How geranylgeraniol supports muscle growth and repair:

Promotes Muscle Growth
- Stimulates the formation of new muscle cells from muscle stem cells
- Increases the activity of key proteins that drive muscle cell formation

Prevents Muscle Breakdown
- Blocks the action of proteins that cause muscle wasting
- Helps maintain muscle mass and size, especially during periods of inactivity or injury

Enhances Muscle Function
- Improves muscle strength and endurance
- Supports energy production within muscle cells by boosting mitochondrial function

In essence, geranylgeraniol facilitates the building of new muscle tissue while simultaneously protecting existing muscle from breakdown. It also optimizes muscle performance by providing the energy needed for muscle contraction and activity. Through these mechanisms, geranylgeraniol creates an environment conducive for overall muscle growth and repair.

Yes, by supporting the production of Coenzyme Q10, a compound that helps generate energy in your cells, GG-PRIME™ can potentially enhance your overall energy levels, especially beneficial for those experiencing fatigue related to statin use.

We stand by a risk-free 60 day money back guarantee. If you are not satisfied with your results we will refund your purchase.

We only ask that you give GG-PRIME™ time to work for you. We believe the product has the potential to help millions Live Better with Statins.

No, our softgels are made with gelatin, which is derived from animal sources. This is common among most types of softgels.

We are confident you will experience the GG-PRIME™ difference. If you are unsatisfied with the results after using GG-PRIME™, we offer a 60-day money-back guarantee on your first order of GG-PRIME™.

We only ask that you give GG-PRIME™ a chance to work. Once your order is delivered, please allow 14 days for it to work its magic. If, after 14 days, you don't feel the difference, contact us at info@gg-prime.com with your order number, and we will refund your original purchase.